Cancer drugs could fight autoimmune disease

日期:2019-03-02 03:02:03 作者:第五姿殆 阅读:

Many anti-cancer drugs have the unfortunate side-effect of depressing the body’s immune system. So it makes sense that one class of these drugs is being investigated as a way of tackling autoimmune diseases like multiple sclerosis and rheumatoid arthritis. These are triggered when the immune system’s T-cells go into overdrive and attack the body’s own cells. Wayne Hancock and colleagues at the Children’s Hospital of Philadelphia have now discovered that histone deacetylase (HDAC) inhibitors – drugs approved for treating cancers like lymphomas – stimulate a specific class of immune cells called regulatory T-cells. These control the activity of other immune …